
3D structures will be determined using X-ray diffraction from single protein crystals. We have regular access to the ESRF synchrotron and are at 5 minutes from the future SOLEIL beamlines. This step is highly technical and experimental conditions and prices have to be negotiated with the costumer for every individual protein considering the available information already gathered by the user.
Available services:
harvesting and cryocooling of crystals
test of diffraction quality
full dataset recording and data processing
structure solution using various methodologies (SIR, SAD, MAD, MR...)
structure analysis.
Expertise at any steps can be provided, for example help with solving the structure from already recorded data.
Contact: Nicolas.Leuliot@ibbmc.u-psud.fr