The box H/ACA RNP assembly factor Naf1p contains a domain homologous to Gar1p mediating its interaction with Cbf5p.
Leulliot N, Godin KS, Hoareau-Aveilla C, Quevillon-Cheruel S, Varani G, Henry Y, Van Tilbeurgh H.
J Mol Biol. 2007 Aug 31;371(5):1338-53.
Crystal structure of AFV3-109, a highly conserved protein from crenarchaeal viruses.
Keller J, Leulliot N, Cambillau C, Campanacci V, Porciero S, Prangishvilli D, Forterre P, Cortez D, Quevillon-Cheruel S, van Tilbeurgh H.
Virol J. 2007 Jan 22;4:12.
Implementation of semi-automated cloning and prokaryotic expression screening: the impact of SPINE
Alzari PM, Berglund H, Berrow NS, Blagova E, Busso D, Cambillau C, Campanacci V, Christodoulou E, Eiler S, Fogg MJ, Folkers G, Geerlof A, Hart D, Haouz A, Herman MD, Macieira S, Nordlund P, Perrakis A, Quevillon-Cheruel S, Tarandeau F, van Tilbeurgh H, Unger T, Luna-Vargas MP, Velarde M, Willmanns M, Owens RJ.
Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1103-13.
Recombinant protein expression and solubility screening: a comparative study
Berrow NS, Bussow K, Coutard B, Diprose J, Ekberg M, Folkers GE, Levy N, Lieu V, Owens RJ, Peleg Y, Pinaglia C, Quevillon-Cheruel S, Salim L, Scheich C, Vincentelli R, Busso D.
Acta Crystallogr D Biol Crystallogr. 2006 Oct;62(Pt 10):1218-26.
Cloning, production and purification of proteins for a small scale structural genomics project
Bruno Collinet, Lionel Trésaugues, Philippe Minard, Gilles Henkes, Robert Aufrère, Karine Blondeau, Nabila Bettache, Cong-Zhao Zhou, Dominique Liger, Joël Janin, Anne Poupon, Herman van Tilbeurgh and Sophie Quevillon-Cheruel
Methods Mol Biol. 2007;363:21-37.
Crystallization and preliminary X-ray diffraction analysis of protein 14 from Sulfolobus islandicus filamentous virus (SIFV)
Goulet A, Spinelli S, Campanacci V, Porciero S, Blangy S, Garrett RA, van Tilbeurgh H, Leulliot N, Basta T, Prangishvili D, Cambillau C.
Acta Crystallograph Sect F Struct Biol Cryst Commun. 2006 Sep 1;62(Pt 9):884-6.
Structure-based functional annotation: Yeast ymr099cp codes for a D-hexose-6-phosphate mutarotase
Graille M, Baltaze JP, Leulliot N, Liger D, Quevillon-Cheruel S, van Tilbeurgh H.
J Biol Chem. 2006 Oct 6;281(40):30175-85.
Crystal structure of the yeast His6 enzyme suggests a reaction mechanism.
Quevillon-Cheruel S, Leulliot N, Graille M, Blondeau K, Janin J, van Tilbeurgh H.
Protein Sci. 2006 Jun;15(6):1516-21
Structural characterization of Set1 RNA recognition motifs and their role in histone H3 lysine 4 methylation.
Tresaugues L, Dehe PM, Guerois R, Rodriguez-Gil A, Varlet I, Salah P, Pamblanco M, Luciano P, Quevillon-Cheruel S, Sollier J, Leulliot N, Couprie J, Tordera V, Zinn-Justin S, Chavez S, van Tilbeurgh H, Geli V.
J Mol Biol. 2006 Jun 23;359(5):1170-81.
Crystal structure of the yeast His6 enzyme suggests a reaction mechanism
Quevillon-Cheruel S, Leulliot N, Graille M, Blondeau K, Janin J, van Tilbeurgh H.
Protein Sci. 2006 Jun;15(6):1516-21.
Crystal structure and confirmation of the alanine:glyoxylate aminotransferase activity of the YFL030w yeast protein.
Meyer P, Liger D, Leulliot N, Quevillon-Cheruel S, Zhou CZ, Borel F, Ferrer JL, Poupon A, Janin J, van Tilbeurgh H.
Biochimie. 2005 Dec;87(12):1041-7.
Crystal structure of yeast YER010Cp, a knotable member of the RraA protein family.
Leulliot N, Quevillon-Cheruel S, Graille M, Schiltz M, Blondeau K, Janin J, Van Tilbeurgh H.
Protein Sci. 2005 Oct;14(10):2751-8.
Crystal structure of the S. cerevisiae D-ribose-5-phosphate isomerase: comparison with the archaeal and bacterial enzymes.
Graille M, Meyer P, Leulliot N, Sorel I, Janin J, Van Tilbeurgh H, Quevillon-Cheruel S.
Biochimie 2005 Aug;87(8):763-9.
Crystal structure of YHI9, the yeast member of the phenazine biosynthesis PhzF enzyme superfamily
Liger D, Quevillon-Cheruel S, Sorel I, Bremang M, Blondeau K, Aboulfath I, Janin J, van Tilbeurgh H, Leulliot N.
Proteins 2005, 60:778-86.
High-throughput crystal-optimization strategies in the South Paris Yeast Structural Genomics Project: one size fits all?
Leulliot N, Tresaugues L, Bremang M, Sorel I, Ulryck N, Graille M, Aboulfath I, Poupon A, Liger D, Quevillon-Cheruel S, Janin J, van Tilbeurgh H.}
Acta Crystallogr D Biol Crystallogr. 2005 61(Pt 6):664-70.
Crystal structure of yeast YHR049W/FSH1, a member of the serine hydrolase family.
Quevillon-Cheruel S, Leulliot N, Graille M, Hervouet N, Coste F, Benedetti H, Zelwer C, Janin J, Van Tilbeurgh H.
Protein Sci. 2005 14(5):1350-6.
Crystal structure of the YML079w protein from Saccharomyces cerevisiae reveals a new sequence family of the jelly-roll fold.
Zhou CZ, Meyer P, Quevillon-Cheruel S, De La Sierra-Gallay IL, Collinet B, Graille M, Blondeau K, Francois JM, Leulliot N, Sorel I, Poupon A, Janin J, Van Tilbeurgh H
Protein Sci. 2005 Jan;14(1):209-15.
The Paris-Sud yeast structural genomics pilot-project: from structure to function
Quevillon-Cheruel S, Liger D, Leulliot N, Graille M, Poupon A, de La Sierra-Gallay IL, Zhou CZ, Collinet B, Janin J, Van Tilbeurgh H
Biochimie. 2004 Sep-Oct;86(9-10):617-23.
Refolding strategies from inclusion bodies in a structural genomics project
Tresaugues L, Collinet B, Minard P, Henckes G, Aufrere R, Blondeau K, Liger D, Zhou CZ, Janin J, Van Tilbeurgh H, Quevillon-Cheruel S
J Struct Funct Genomics. 2004;5(3):195-204.
Crystal structure and functional characterization of yeast YLR011wp, an enzyme with NAD(P)H-FMN and ferric iron reductase activities
Liger D, Graille M, Zhou CZ, Leulliot N, Quevillon-Cheruel S, Blondeau K, Janin J, van Tilbeurgh H
J Biol Chem. 2004 Aug 13;279(33):34890-7.
Crystal structure of the YDR533c S. cerevisiae protein, a class II member of the Hsp31 family.
Graille M, Quevillon-Cheruel S, Leulliot N, Zhou CZ, de la Sierra Gallay IL, Jacquamet L, Ferrer JL, Liger D, Poupon A, Janin J, van Tilbeurgh H
Structure (Camb). 2004 May;12(5):839-47.
Crystal structure of yeast allantoicase reveals a repeated jelly roll motif
Leulliot N, Quevillon-Cheruel S, Sorel I, Graille M, Meyer P, Liger D, Blondeau K, Janin J, van Tilbeurgh H.
J Biol Chem. 2004 May 28;279(22):23447-52.
Crystal structure of the YGR205w protein from Saccharomyces cerevisiae: close structural resemblance to E. coli pantothenate kinase
de La Sierra-Gallay IL, Collinet B, Graille M, Quevillon-Cheruel S, Liger D, Minard P, Blondeau K, Henckes G, Aufrere R, Leulliot N, Zhou CZ, Sorel I, Ferrer JL, Poupon A, Janin J, van Tilbeurgh H
Proteins. 2004 Mar 1;54(4):776-83.
Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity
Leulliot N, Quevillon-Cheruel S, Sorel I, de La Sierra-Gallay IL, Collinet B, Graille M, Blondeau K, Bettache N, Poupon A, Janin J, van Tilbeurgh H
J Biol Chem. 2004 Feb 27;279(9):8351-8.
Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae
Quevillon-Cheruel S, Leulliot N, Meyer P, Graille M, Bremang M, Blondeau K, Sorel I, Poupon A, Janin J, van Tilbeurgh H
J Biol Chem. 2004 Jan 2;279(1):619-25.
Crystal structure of the yeast Phox homology (PX) domain protein Grd19p complexed to phosphatidylinositol-3-phosphate.
Zhou CZ, de La Sierra-Gallay IL, Quevillon-Cheruel S, Collinet B, Minard P, Blondeau K, Henckes G, Aufrere R, Leulliot N, Graille M, Sorel I, Savarin P, de la Torre F, Poupon A, Janin J, van Tilbeurgh H
J Biol Chem. 2003 Dec 12;278(50):50371-6.
A structural genomics initiative on yeast proteins
Quevillon-Cheruel S, Collinet B, Zhou CZ, Minard P, Blondeau K, Henkes G, Aufrere R, Coutant J, Guittet E, Lewit-Bentley A, Leulliot N, Ascone I, Sorel I, Savarin P, de La Sierra Gallay IL, de la Torre F, Poupon A, Fourme R, Janin J, van Tilbeurgh H.
J Synchrotron Radiat. 2003 Jan 1;10(Pt 1):4-8. Epub 2002 Dec 24.
The yeast ribosome synthesis factor Emg1 is a novel member of the superfamily of alpha/beta knot fold methyltransferases.
Leulliot N, Bohnsack MT, Graille M, Tollervey D, Tilbeurgh HV.
Nucleic Acids Res. 2007 Dec 6 [Epub ahead of print]Click here to read
Structure of yeast Dom34: a protein related to translation termination factor eRF1 and involved in No-Go decay.
Graille M, Chaillet M, van Tilbeurgh H.
J Biol Chem. 2008 Jan 7 [Epub ahead of print]Click here to read
Structure of the Yeast tRNA m7G Methylation Complex
Leulliot N, Chaillet M, Durand D, Ulryck N, Blondeau K, van Tilbeurgh H.
Structure. 2008 Jan 8;16(1):52-61.Click here to read
The rolling-circle plasmid pTN1 from the hyperthermophilic archaeon Thermococcus nautilus.
Soler N, Justome A, Quevillon-Cheruel S, Lorieux F, Le Cam E, Marguet E, Forterre P.
Mol Microbiol. 2007 Oct;66(2):357-70.
An archaeal orthologue of the universal protein Kae1 is an iron metalloprotein which exhibits atypical DNA-binding properties and apurinic-endonuclease activity in vitro.
Hecker A, Leulliot N, Gadelle D, Graille M, Justome A, Dorlet P, Brochier C, Quevillon-Cheruel S, Cam EL, Tilbeurgh HV, Forterre P.
Nucleic Acids Res. 2007 Sep 6; [Epub ahead of print]
Encapsulation of mono- and oligo-nucleotides into aqueous-core nanocapsules in presence of various water-soluble polymers.
Hillaireau H, Le Doan T, Chacun H, Janin J, Couvreur P.
Int J Pharm. 2007 Mar 1;331(2):148-52.
Crystal structure of the yeast cytoplasmic thioredoxin Trx2.
Bao R, Chen Y, Tang YJ, Janin J, Zhou CZ.
Proteins. 2007 Jan 1;66(1):246-9.
Pichia pastoris is a valuable host for the expression of genes encoding membrane proteins from the hyperthermophilic Archeon Pyrococcus abyssi.
Labarre C, van Tilbeurgh H, Blondeau K.
Extremophiles. 2006 Nov 8; [Epub ahead of print]
Crystal structure of the yeast cytoplasmic thioredoxin Trx2
Bao R, Chen Y, Tang YJ, Janin J, Zhou CZ.
Proteins. 2006 Oct 16; [Epub ahead of print]
Encapsulation of antiviral nucleotide analogues azidothymidine-triphosphate and cidofovir in poly(iso-butylcyanoacrylate) nanocapsules.
Hillaireau H, Le Doan T, Besnard M, Chacun H, Janin J, Couvreur P.
Int J Pharm. 2006 Oct 31;324(1):37-42.
The zinc-finger protein Ynr046w is plurifunctional and a component of the eRF1 methyltransferase in yeast.
Heurgue-Hamard V, Graille M, Scrima N, Ulryck N, Champ S, van Tilbeurgh H, Buckingham RH.
J Biol Chem. 2006 Nov 24;281(47):36140-8.
Catalytic mechanism and structure of viral flavin-dependent thymidylate synthase ThyX
Graziani S, Bernauer J, Skouloubris S, Graille M, Zhou CZ, Marchand C, Decottignies P, van Tilbeurgh H, Myllykallio H, Liebl U.
J Biol Chem. 2006 Aug 18;281(33):24048-57.
The HSP90 and DNA topoisomerase VI inhibitor radicicol also inhibits human type II DNA topoisomerase.
Gadelle D, Graille M, Forterre P.
Biochem Pharmacol. 2006 Nov 15;72(10):1207-16.
Crystal structure of the PP2A phosphatase activator: implications for its PP2A-specific PPIase activity.
Leulliot N, Vicentini G, Jordens J, Quevillon-Cheruel S, Schiltz M, Barford D, van Tilbeurgh H, Goris J.}
Mol Cell. 2006 Aug 4;23(3):413-24.
Structure of the human multidrug resistance protein 1 nucleotide binding domain 1 bound to Mg2+/ATP reveals a non-productive catalytic site
Ramaen O, Leulliot N, Sizun C, Ulryck N, Pamlard O, Lallemand JY, Tilbeurgh H, Jacquet E.
J Mol Biol. 2006 Jun 16;359(4):940-9.
Structures of in vitro evolved binding sites on neocarzinostatin scaffold reveal unanticipated evolutionary pathways
Drevelle A, Graille M, Heyd B, Sorel I, Ulryck N, Pecorari F, Desmadril M, van Tilbeurgh H, Minard P.
J Mol Biol. 2006 Apr 28;358(2):455-71.
sHSPs under temperature and pressure: The opposite behaviour of lens alpha-crystallins and yeast HSP26.
Skouri-Panet F, Quevillon-Cheruel S, Michiel M, Tardieu A, Finet S.
Biochim Biophys Acta. 2006 Mar;1764(3):372-83.
Molecular basis for bacterial class I release factor methylation by PrmC
Graille M, Heurgue-Hamard V, Champ S, Mora L, Scrima N, Ulryck N, van Tilbeurgh H, Buckingham RH.
Mol Cell 2005 Dec 22;20(6):917-27.
Cyc2p, a membrane-bound flavoprotein involved in the maturation of mitochondrial c-type cytochromes.
Bernard DG, Quevillon-Cheruel S, Merchant S, Guiard B, Hamel PP.
J Biol Chem. 2005 Dec 2;280(48):39852-9.
Activation of the LicT transcriptional antiterminator involves a domain swing/lock mechanism provoking massive structural changes
Graille M, Zhou CZ, Receveur-Brechot V, Colinet B, Declerck N, van Tilbeurgh H
J. Biol. Chem 2005 Apr 15;280(15):14780-9.
Inhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicol.
Gadelle D, Bocs C, Graille M, Forterre P.
Nucleic Acids Res. 2005 Apr 22;33(7):2310-7.
A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III
Leulliot N, Quevillon-Cheruel S, Graille M, Van Tilbeurgh H, Leeper TC, Godin KS, Edwards TE, Sigurdsson ST, Rozenkrants N, Nagel RJ, Ares M, Varani G
EMBO J. 2004 Jul 7;23(13):2468-2477.
Structural inhibition of the colicin D tRNase by the tRNA-mimicking immunity protein
Graille M, Mora L, Buckingham RH, Van Tilbeurgh H, De Zamaroczy M
EMBO J. 2004 Apr 7;23(7):1474-82.
The solution structure of an essential stem-loop of human telomerase RNA.
Leeper T, Leulliot N, Varani G
Nucleic Acids Res. 2003 May 15;31(10):2614-21.
Structural insights into the regulation of bacterial signalling proteins containing PRDs
van Tilbeurgh H, Declerck N
Curr Opin Struct Biol. 2001 Dec;11(6):685-93.
Dimer stabilization upon activation of the transcriptional antiterminator LicT.
Declerck N, Dutartre H, Receveur V, Dubois V, Royer C, Aymerich S, van Tilbeurgh H
J Mol Biol. 2001 Dec 7;314(4):671-81
Crystal structure of maltose phosphorylase from Lactobacillus brevis: unexpected evolutionary relationship with glucoamylases
Egloff MP, Uppenberg J, Haalck L, van Tilbeurgh H
Structure (Camb). 2001 Aug;9(8):689-97
Crystal structure of an activated form of the PTS regulation domain from the LicT transcriptional antiterminator
van Tilbeurgh H, Le Coq D, Declerck N
EMBO J. 2001 Jul 16;20(14):3789-99.
Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast
Ganem C, Devaux F, Torchet C, Jacq C, Quevillon-Cheruel S, Labesse G, Facca C, Faye G.
EMBO J. 2003 Apr 1;22(7):1588-98.
Analysis and prediction of protein quaternary structure
Anne Poupon & Joël Janin
Methods in Molecular Biology, in press.
Mesures Hiérarchiques pondérées pour l’évaluation d’ un système semi-automatique d’annotation de génomes utilisant des arbres de décision
Lucie Gentils, Jérôme Azé, Claire Toffano-Nioche, Valentin Loux, Anne Poupon, Jean-François Gibrat, Christine Froidevaux
Proceedings de EGC 2008
The VIZIER project: Preparedness against pathogenic RNA viruses.
Coutard B, Gorbalenya AE, Snijder EJ, Leontovich AM, Poupon A, De Lamballerie X, Charrel R, Gould EA, Gunther S, Norder H, Klempa B, Bourhy H, Rohayem J, L’hermite E, Nordlund P, Stuart DI, Owens RJ, Grimes JM, Tucker PA, Bolognesi M, Mattevi A, Coll M, Jones TA, Aqvist J, Unge T, Hilgenfeld R, Bricogne G, Neyts J, La Colla P, Puerstinger G, Gonzalez JP, Leroy E, Cambillau C, Romette JL, Canard B.
Antiviral Res. 2008 Apr;78(1):37-46
DiMoVo: a Voronoi tessellation-based method for discriminating crystallographic and biological protein-protein interactions.
Bernauer J, Bahadur RP, Rodier F, Janin J, Poupon A.
Bioinformatics. 2008 Mar 1;24(5):652-8
Towards a semi-automatic functional annotation tool based on decision tree techniques
J. Azé, L. Gentils, C. Toffano-Nioche, V. Loux, J-F. Gibrat, P. Bessières, C. Rouveirol, A. Poupon, and C. Froidevaux
In Proceedings of the International Conference on Machine Learning in Systems Biology (MLSB 2007), in press
The targets of CAPRI rounds 6-12.
Janin J.
Proteins. 2007 Aug 1; [Epub ahead of print]
The third CAPRI assessment meeting Toronto, Canada, April 20-21, 2007.
Janin J, Wodak S.
Structure. 2007 Jul;15(7):755-9
Production and crystallization of protein domains: how useful are disorder predictions ?
S. Quevillon-Cheruel, N. Leulliot, L. Gentils, H. van Tilbeurgh and A. Poupon
Curr Protein Pept Sci. 2007 Apr;8(2):151-60. Review.
Data Management in Structural Genomics: an Overview
S. Haquin, E. Oeuillet, A. Pajon, M. Harris, A.T. Jones, H. van Tilbeurgh, J.L. Markley, Z. Zolnai, and A. Poupon
Methods in Molecular Biology, in press.
A new protein-protein docking scoring function based on interface residue properties
Bernauer J, Aze J, Janin J, Poupon A.
Bioinformatics. 2007 Mar 1;23(5):555-62
A dissection of the protein-protein interfaces in icosahedral virus capsids.
Bahadur RP, Rodier F, Janin J.
J Mol Biol. 2007 Mar 23;367(2):574-90.
Macromolecular recognition in the Protein Data Bank.
Janin J, Rodier F, Chakrabarti P, Bahadur RP.
Acta Crystallogr D Biol Crystallogr. 2007 Jan;63(Pt 1):1-8.
Peptide segments in protein-protein interfaces.
Pal A, Chakrabarti P, Bahadur R, Rodier F, Janin J.
J Biosci. 2007 Jan;32(1):101-11.
Accuracy and reliability in modelling proteins and complexes
Joël Janin and Michael Levitt
Curr Opin Struct Biol. (2006)16, 1-3.
Revisiting the Voronoi description of protein-protein interfaces.
Cazals F, Proust F, Bahadur RP, Janin J.
Protein Sci. 2006 Sep;15(9):2082-92.Click here to read
Une nouvelle fonction de score pour l’amarrage protéine-protéine fondée sur les diagrammes de Voronoï
Julie Bernauer, Jérôme Azé, Joël Janin, Anne Poupon
Proceedings de JOBIM 2005
HalX: an open-source LIMS (Laboratory Information Management System) for small to large scale labs
Jaime Prilusky, Eric Oeuillet, Nathalie Ulryck, Anne Pajon, Julie Bernauer, Isabelle Krimm, Sophie Quevillon-Cheruel, Nicolas Leulliot, Marc Graille, Dominique Liger, Lionel Trésaugues, Joel L. Sussman, Joël Janin, Herman van Tilbeurgh, and Anne Poupon
Acta Crystallogr D Biol Crystallogr. 2005 Jun;61(Pt 6):671-8.
A docking analysis of the statistical physics of protein protein recognition
Julie Bernauer, Anne, Poupon, Jerome Aze, Joel Janin
Physical Biology, 2005, 2, S17-S23
Prediction of unfolded segments in a protein sequence based on amino acid composition
Karen Coeytaux and Anne Poupon
Bioinformatics 2005 21: 1891 - 1900.
Design of a data model for developing laboratory information management and analysis systems for protein production
Pajon A, Ionides J, Diprose J, Fillon J, Fogh R, Ashton AW, Berman H, Boucher W, Cygler M, Deleury E, Esnouf R, Janin J, Kim R, Krimm I, Lawson CL, Oeuillet E, Poupon A, Raymond S, Stevens T, van Tilbeurgh H, Westbrook J, Wood P, Ulrich E, Vranken W, Xueli L, Laue E, Stuart DI, Henrick K
Proteins. 2005 Feb 1;58(2):278-84.
Voronoi and Voronoi-related tessellations in studies of protein structure and interaction
Poupon A
Curr Opin Struct Biol. 2004 Apr;14(2):233-41. Review.
Origin and evolution of transmembrane Chl-binding proteins: hydrophobic cluster analysis suggests a common one-helix ancestor for prokaryotic (Pcb) and eukaryotic (LHC) antenna protein superfamilies
Garczarek L, Poupon A, Partensky F
FEMS Microbiol Lett. 2003 May 16;222(1):59-68.
Exp-DB: Fast Development of Information
Naem NA, Raymond S, Poupon A, Cygler M, Kemme B
CAiSE Short Paper Proceedings 2003
